At MetroSpa, we’re committed to offering only the most advanced and clinically proven skin rejuvenation treatments, and one of the most exciting innovations in regenerative aesthetics right now is Plinest Polynucleotides.
Recently crowned Injectable Product of the Year at the 2025 Aesthetic Awards, Plinest is rapidly becoming one of the most in-demand treatments for patients seeking natural, long-lasting skin regeneration without adding volume or changing facial shape.
Polynucleotides are biological molecules derived from DNA fragments, and they’re designed to repair, regenerate and revitalise the skin at a cellular level. When injected into the skin, polynucleotides work by:
The result? Healthier, firmer, and more radiant skin, restored from the inside out.
Plinest is the original and most scientifically studied polynucleotide brand, developed by Mastelli, pioneers in regenerative medicine with over 70 years of research.
It’s the only polynucleotide brand derived from ultra-purified salmon DNA using HPT™ (High Purification Technology), making it exceptionally safe, biocompatible and effective.
Plinest was named Injectable Product of the Year at the 2025 Aesthetic Awards, solidifying its status as the go-to regenerative injectable for medical aesthetic professionals across the UK and beyond.
Plinest is ideal for patients who are experiencing:
It’s suitable for use on the face, neck, décolletage, under-eyes, and even the scalp.
Unlike traditional injectables such as dermal fillers or skin boosters, Plinest doesn’t add volume. Instead, it supports your body’s natural repair processes, creating stronger, more resilient skin over time.
Benefits of Plinest include:
Most patients begin with a course of 3–4 sessions spaced 2–3 weeks apart, followed by maintenance treatments every few months, depending on skin goals.
Improvements in hydration, skin texture, elasticity and glow can often be seen within a few weeks, with results continuing to build as collagen and elastin synthesis increases.
At MetroSpa, we specialise in regenerative aesthetics, and our expert team is highly trained in delivering advanced injectables like Plinest. We offer a bespoke, medically-led approach that ensures each treatment plan is tailored to your skin’s unique needs.
Our clinic in Birmingham offers a serene and professional setting where innovation meets results, and with our focus on medical-grade skincare and science-backed technology, Plinest is a natural fit within our treatment portfolio.
If you’re ready to restore skin quality from the inside out with one of the most advanced injectables in aesthetic medicine, it’s time to try Plinest at MetroSpa. Book your consultation with our expert team in Birmingham today and discover the power of polynucleotides.
